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What Is The Problem With Depression Medication ?

  • Posted on July 1, 2009 at 7:36 pm

The main issue with depression medication is that it is a hit and miss affair. The first problem is that as the drug companies are not exactly sure how these medications work on the brain, results can vary enormously from individual to individual. The second problem is that these drugs work mainly on increasing serotonin which is fine except that serotonin is also responsible for controlling our appetite. Weight gain and weight loss will figure prominently as a result among the side effects. The third problem is that overall, while some patients will gain a lot of benefit from this depression medication, many will never be cured and face years of treatment with very modest results.

The earlier anti depression medication like the tricyclics and the Monoamine oxidase inhibitors (MAOIs) such as Marplan and Nardil were even riskier and with the latter patients had to avoid dairy and alcohol as there was a dangerous interaction with the drugs. The newer drugs (the SSRIs) are much safer overall and there are certainly less alarming side effects but there is still a long list to deal with.

With SSRIs, such as Luvox, Paxil, Prozac and Zoloft, the main side effect seems to be a loss of sex drive and impotence in men while women will have problems in reaching orgasm. Other problems are with weight gain, nausea and jittery feelings. Add to those insomnia , headaches and vertigo and you will see that taking these medicines is no picnic. Reactions will vary from person to person and some people manage to cope with the side effects with greater ease and confidence without falling into further depression ! Are these drugs anti depression medication or not?

A newer drug called Wellbutrin has been used with some success and it seems to avoid some of the sexual problems associated with the drugs mentioned above and also the problem of putting on weight. This drug acts on two of the neurotransmitters in the brain, norepinephrine and dopamine. But Wellbutrin has its own problems in that it can actually reduce appetite so patients are faced with weight loss, constipation, insomnia, anxiety, diarrhea, drowsiness and dry mouth.

Yet a newer class of depression medication which increases levels of serotonin and norepinephrine such as Cymbalta and Remeron fare only a little better but still have a fairly daunting list of possible side effects. These include blurred vision, tremor, chills and feeling lightheaded. Cymbalta can raise blood pressure, increase sweating and loss of energy.

You can see why thousands of people are seeking alternatives to depression medication. One answer has been found in natural treatment for depression with herbal remedies. Research shows that in many cases , especially with mild and moderate depression and SAD (seasonal affective disorder), these remedies are just as effective as the classic depression medication and have much fewer side effects.

Want to learn what is the problem with depression medication ? Robert Locke has written extensively on Mental Health for many years.

Article Source: What Is The Problem With Depression Medication ?

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Atypical Depression

  • Posted on July 1, 2009 at 7:36 pm

Atypical depression, a subtype of major depression, is the most common form of depression today. People who suffer atypical depression exhibit all the normal symptoms of depression but they also react to external positive experiences in a positive way. Atypical depression sufferers respond to their environment, enjoying the company of friends but slipping back into deep depression when alone or faced with a stressful situation. It is this aspect of atypical depression that differentiates it from melancholic depression in which external positive experiences still result in depressed feelings.

People who suffer from atypical depression also exhibit other symptoms that aren’t normally associated with “normal” depression including:

• Increase in appetite with a weight gain of ten or more pounds.
• Hypersomnia -over sleeping of more than 10 hours per day.
• Leaden paralysis of the arms and legs
• Long term pattern of sensitivity to rejection in personal situations that causes social or work related withdrawal.

In 1998 Dr. Andrew A. Nierenberg, associate director of the depression clinical and research program at Massachusetts General Hospital, published a study that found 42% of participants suffered from atypical depression, 12% had melancholic depression, 14% had both depression subtypes and the remaining did not suffer from depression.

Studies have also found that atypical depression begins earlier in a person’s life than other forms of depression with most sufferers beginning to show symptoms in their teenage years. Those who suffer from atypical depression are also at greater risk of suffering from other mental disorders such as social phobias, avoidant personality disorder or body dysmorphic disorder. Atypical depression is more prevalent in females than males as well, with nearly 70% of it’s sufferers being women.

Treating atypical depression is an ongoing process. Research has shown that MAOIs such as Nardil or Parnate work reasonably well as do the newer SSRI medications (Lexapro, Prozac, Zoloft). Most patients prefer the SSRIs because they do not exhibit the unpleasant side affects of the MAOIs.

It is also important that if you or someone you know suffers from atypical depression that you or they seek psychiatric help. Atypical depression is not easy to diagnose the treatment choices can vary from patient to patient. A general care practitioner does not have the expertise to differentiate between the subtypes of depression and may not know the best course of treatment for their patient.

Andrew Bicknell is a writer and Webmaster of Depression and You.com. Visit his website for more information about Atypical Depression and other depression disorders.

Article Source: Atypical Depression

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